/ / Toxicoderma. Causes, methods of treatment and prevention

Toxicoderma. Causes, methods of treatment and prevention

In the prevalence, there is a limited and widespread form of toxicodermia, by the nature of the rashes - spotty, papular, nodular, vesiculose, pustular, bullous and necrotic.
In addition to the skin, rashes can also be localized on the mucous membranes. Often, the general condition of patients is disturbed, the body temperature rises.

Restricted (fixed) toxicodermiaIs manifested by the sudden appearance of one or more bright red spots with a diameter of up to 5 cm. After resolution, they leave a stable brown pigmentation. Often, limited toxicoderma is localized on the skin of the anogenital area and mucous membranes. Bubbles can appear on the lesions, and in case of damage, painful erosion. After stopping the intake of the allergen, the rash disappears after 10-14 days.

Diffuse (common) toxicodermiaIs considered a serious skin disease. Its development is accompanied by fever, dyspepsia, adynamia. Rashes are predominantly polymorphic. They can resemble manifestations of eczema, hives, bullous dermatoses.

Spotted toxicosis is accompanied by the appearance ofHyperergic, hemorrhagic and pigmented spots on the skin surface. It manifests itself first on the skin of the forehead, cheekbones and temples, then - on the extensor surfaces of the limbs and trunk. On the spot of the spots there is peeling erythema. Against the background of erythema develops a network pigmentation or follicular keratosis.

Papular toxicoderm is characterized by the appearance of oval miliary papules at the site of the lesion. They can peripherally grow and merge, forming plaques.

Knotty toxicodermia is characterized by the appearance of painful knots, which slightly protrude above the level of healthy skin.

With vesicular toxicoderma, polymorphic vesicles (vesicles) appear on the skin.

Pustular toxicodermia occurs due toHypersensitivity to halogens (fluoride, chlorine, bromine, iodine), group B vitamins, some medications. In addition to pustules, small eels may appear on the skin of the face and upper body.

Bullous toxicoderma is manifested mainly on the skin of the neck, large folds, on the mucous membranes. Around the bubbles there is a characteristic red border.

Necrotic toxicodermia develops in the backgroundAcute infectious diseases or as a reaction to drugs. The disease develops sharply. On the skin and mucous membranes, red spots appear, against which background bubbles form. The latter are easily destroyed and infected.

For successful treatment of toxicodermia, you needTo eliminate contact with an allergic factor. Assign antihistamine, desensitizing and diuretics, ascorbic acid. In food genesis, diseases are performed by lavage of the stomach, and enterosorbents are prescribed. For local treatment, anti-burn aerosols ("Olazol", "Panthenol"), glucocorticosteroid ointments are used. Erosions are treated with 1% solution of potassium permanganate, fucorcin. With a significant spread of lesions and resistance to therapy, glucocorticosteroids are administered orally and parenterally. The dose is selected individually.

Prophylaxis of toxicodermia consists in prescribing medications taking into account their tolerability in the past, avoiding contact with known allergens.
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