Vaccination of children against influenza
Vaccines against influenza
Vaxigrip - split vaccine (purified inactivated)Produced by the French company Pasteur Merri Connaught. One vaccination dose contains a minimum of fifteen micrograms of hemagglutinin H3N2-influenza A virus, 15 μg (not less) hemagglutinin of the H1N1 virus-influenza A virus, 15 μg (not less) of the hemagglutinin type B virus. In addition, the vaccine dose is contained in a small Amount of formaldehyde, merthiolate, traces of neomycin and buffer solution.
Grippol - polymer-subunit trivalent vaccine(Manufactured by TNK Institute of Immunology, Russia, Moscow), which contains surface antigens of influenza A (H3N2 and H1N1) and influenza B, also contain conjugated antigens with a polyoxidonium immunostimulant. All this with a relatively low quantitative presence of antigens significantly increases the immunogenicity of vaccines.
Fluarix - purified inactivated influenzaSplit vaccine, manufactured in Belgium (Smith Klein Beecham). It contains fifteen micrograms of haemagglutinin each strain of the influenza virus, sucrose, phosphate buffer, traces of formaldehyde and merthiolate (all strains are recommended by WHO).
Influwak - subunit inactivated trivalentThe influenza vaccine produced in the Netherlands (Solvay Pharma) contains purified surface antigens to neuraminidase and hemagglutinin, which are derived from important strains of the influenza virus, presented by WHO, taking into account the instability of the virus.
Indications for use
If possible, vaccination against influenza should be received by all children from the age of six months, but vaccination is primarily carried out among children who are at risk. These are kids:
- With pulmonary diseases in chronic form, including patients with severe and moderate asthma, chronic bronchitis;
- With heart disease, especially with significant hemodynamic disorders;
- Receiving immunosuppressive therapy;
- With sickle-cell anemia or other hemoglobinopathies;
- With immunopathology, including with HIV infection;
- With chronic metabolic and renal diseases;
- Patients with diabetes mellitus;
- Taking aspirin for a long time, since after the flu there is a possibility of the development of Ray's syndrome.
Mandatory vaccination of childrenIs held in pre-school institutions, at children's homes and in boarding schools. It should be noted that this vaccination is carried out only at will and with the permission of the parents (the exception are the home of the child).
Vaccination against influenza is carried out independently ofSeason, but it is better to spend in September-November (at this time the influenza season begins). In adults, the inactivated vaccine is administered once, in children it is administered twice (between vaccinations, a 30-day interval).
Precautions and Contraindications
Inactivated live influenza vaccineAre contraindicated for people with hypersensitivity to chicken and egg white. Acute infection can become a temporary contraindication. People with immunodeficiency are vaccinated with inactivated vaccine according to general rules. However, split split vaccines (Fluarix, Vaxigrip), subunit vaccines (Agrippal, Influvac) are administered only at the age of six months. To protect a child who is not yet 6 months old, all who surround him are vaccinated.
Influenza vaccination in children with severePathology is carried out exclusively by a split subunit vaccine. Preparations of the following type are suitable: purified trivalent split vaccines Influvac, Grippol, Vaxigrip, Fluarix.